Show a specific example: "We used Waterfall for regulatory milestones and Agile sprints within each phase for the development work. This gave compliance the checkpoints they needed while giving the team flexibility."
Strong answers show pragmatism: using Agile for development iterations within a Waterfall-style programme plan, or combining Kanban for operations with Scrum for development. Best candidates discuss why pure approaches often fail in practice and how to get the benefits of both without the worst of each.
Tests practical judgment. Real-world projects rarely fit neatly into one methodology. Candidates who can blend approaches pragmatically while maintaining process integrity are the most effective PMs.